Gabapentin leads to remission of somatoform pain disorder with major depression
| Autor: | Iris Maurer, Hans-Peter Volz, Heinrich Sauer |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Pediatrics
medicine.medical_specialty Time Factors Gabapentin Cyclohexanecarboxylic Acids Analgesic Inguinal Canal Pain Acetates medicine Humans Pharmacology (medical) Amines Somatoform Disorders Stabbing Pain Depression (differential diagnoses) gamma-Aminobutyric Acid Depressive Disorder General Medicine Carbamazepine Middle Aged medicine.disease Psychiatry and Mental health medicine.anatomical_structure Anesthesia Major depressive disorder Antidepressant Abdomen Anticonvulsants Female Psychology medicine.drug |
| Zdroj: | Pharmacopsychiatry. 32(6) |
| ISSN: | 0176-3679 |
| Popis: | Gabapentin, a novel antiepileptic drug, is effective in the treatment of partial seizures with and without secondary generalization. Evidence suggests that it may have mood-stabilizing and possibly antidepressant properties in bipolar depression. We report on a 48-year-old woman who had recurrent major depressive disorder. Following inguinal herniorrhaphy, she developed severe stabbing pain in the lower abdomen and inguinal area that progressed to constant pain in her whole body. She was depressive, hopeless, and had given up her social activities. A diagnosis of major depressive disorder and somatoform pain disorder was made. Antidepressants and carbamazepine were ineffective, and she had attempted suicide. Gabapentin resulted in remission of both the pain and the depressive mood at a dose of 1.800 mg/day. |
| Databáze: | OpenAIRE |
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