Variations of Nighttime and Daytime Bladder Capacity in Patients with Nocturia: Implication for Diagnosis and Treatment
| Autor: | Fabrizio Presicce, Alberto Melchionna, Cosimo De Nunzio, Riccardo Lombardo, Andrea Tubaro, Federica Puccini |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Urology Urinary Bladder 030232 urology & nephrology Bladder capacity urologic and male genital diseases aging lower urinary tract symptoms nocturia ponfidence Intervals female humans male middle aged multivariate analysis odds ratio polyuria prognosis Prosolyuria urinary bladder aged circadian rhythm cohort studies Cpective studies severity of Illness Index time factors urodynamics Severity of Illness Index Cohort Studies 03 medical and health sciences Urine production 0302 clinical medicine Polyuria Lower urinary tract symptoms Confidence Intervals Odds Ratio medicine Humans Nocturia In patient Prospective Studies Aged Urinary bladder business.industry Middle Aged Prognosis medicine.disease female genital diseases and pregnancy complications Circadian Rhythm Urodynamics medicine.anatomical_structure Multivariate Analysis Female medicine.symptom business |
| Zdroj: | Journal of Urology. 201:962-966 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1097/ju.0000000000000022 |
| Popis: | We subtyped patients with nocturia according to daily variations in urine production and bladder capacity.Patients with 1 or more nocturia episodes per day were prospectively enrolled in this study. Post-void residual urine was collected and a 3-day frequency-volume chart was created. Nocturnal polyuria and bladder capacity were calculated for each patient. Reduced bladder capacity was defined as mean 24-hour bladder capacity less than 200 ml. Patients were categorized into 4 subgroups by the presence or absence of nocturnal polyuria and reduced bladder capacity.Of the 84 patients enrolled in study 50 (59.5%) had nocturnal polyuria and 50 (59.5%) had decreased bladder capacity. Patients with reduced bladder capacity and nocturnal polyuria had significantly greater mean and maximum bladder capacity at night than during the day (p = 0.002) and the highest number of nocturia episodes (3, IQR 2-3). Patients with normal bladder capacity but with nocturnal polyuria had significantly larger mean and maximum bladder capacity at night (p = 0.033 and 0.016, respectively). In patients with reduced bladder capacity and no nocturnal polyuria we observed no significant variation in bladder capacity during the day vs the night. On multivariable analysis the body mass index (OR 1.28 per unit, 95% CI 1.04-1.58, p = 0.019) and severe nocturia (OR 6.26, 95% CI 1.71-22.92, p = 0.006) were risk factors for nocturnal polyuria while only severe nocturia was a predictive factor for reduced bladder capacity (OR 3.77, 95% CI 1.20-11.83, p = 0.023).Patients with nocturnal polyuria have a different bladder capacity in the day and the night. Severe nocturia (3 or more episodes per night) predicts the presence of nocturnal polyuria and reduced bladder capacity. Our data suggest that in patients with severe nocturia those 2 conditions should be considered and managed. |
| Databáze: | OpenAIRE |
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