The lymphatic system and pancreatic cancer
| Autor: | Michael A. Hollingsworth, Darci M. Fink, Maria M. Steele |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Cancer Research Pathology medicine.medical_specialty Lymphovascular invasion medicine.medical_treatment Cell Communication Article Metastasis Lymphatic System 03 medical and health sciences Pancreatectomy 0302 clinical medicine Pancreatic cancer Tumor Microenvironment Animals Humans Medicine Neoplasm Invasiveness Lymphangiogenesis Lymph node Tumor microenvironment business.industry medicine.disease Pancreatic Neoplasms Treatment Outcome 030104 developmental biology Lymphatic system medicine.anatomical_structure Oncology Lymphatic Metastasis 030220 oncology & carcinogenesis Lymph Node Excision business Carcinoma Pancreatic Ductal |
| Zdroj: | Cancer Letters. 381:217-236 |
| ISSN: | 0304-3835 |
| DOI: | 10.1016/j.canlet.2015.11.048 |
| Popis: | This review summarizes current knowledge of the biology, pathology and clinical understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the clinical and biological consequences of lymphatic invasion and metastasis, including paraneoplastic effects on immune responses and consider the possible benefit of therapies to treat tumors that are localized to lymphatics. A review of current techniques and methods to study interactions between tumors and lymphatics is presented. |
| Databáze: | OpenAIRE |
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