Disability among US Army Veterans vaccinated against anthrax
| Autor: | Hayley Hughes, Charles Maynard, Paul J. Amoroso, Edward J. Boyko, Sandra I. Sulsky, Patrick M. Garman, Rose S. Luippold |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Gerontology
Adult Male medicine.medical_specialty Active duty Adolescent Context (language use) Anthrax Vaccines Disability Evaluation Young Adult Disability benefits Epidemiology medicine Humans Young adult Veterans Disability Claims Veterans General Veterinary General Immunology and Microbiology business.industry Vaccination Public Health Environmental and Occupational Health Anthrax Vaccine Adsorbed United States United States Department of Veterans Affairs Infectious Diseases Logistic Models Family medicine Case-Control Studies Cohort Molecular Medicine Female business |
| Zdroj: | Vaccine. 30(43) |
| ISSN: | 1873-2518 |
| Popis: | Context To protect troops against the use of anthrax as a biological weapon, the US Department of Defense began an anthrax vaccination program in 1998. 14 years after the inception of the vaccination program, there is no evidence suggesting vaccination against anthrax carries long-term health risks for Active Duty Soldiers. Objective To investigate the association between Anthrax Vaccine Adsorbed (AVA) received while on Active Duty and subsequent disability determined by the Veterans Benefits Administration. Design, setting and participants Case–control study nested in the cohort of all Active Duty personnel known to have separated from the US Army between December 1, 1997 and December 31, 2005. Cases were ≥10% disabled, determined either by the Army prior to separation ( N = 5846) or by the Veterans Benefits Administration (VBA) after separation ( N = 148,934). Controls ( N = 937,705) separated from the Army without disability, and were not receiving pensions from the VBA as of April 2007. Data were from the Total Army Injury and Health Outcomes Database and the VBA Compensation and Pension and Benefits database. Main outcomes Disability status (yes/no); for primary disability, percent disabled (≥ 10%, 20%, >20%) and type of disability. Results Vaccination against anthrax was four times more likely among disabled Veterans with hostile fire pay records (HFP, a surrogate for deployment). Vaccinated Soldiers with HFP had lower odds of disability separation from the Army 0.89 (0.80, 0.98); there was no association between vaccine and receiving Army disability benefits among those without HFP (OR = 1.05, CI: 0.96, 1.14). Vaccination was negatively associated with receiving VA disability benefits for those with HFP (OR = 0.66, CI: 0.65, 0.67), but there was little or no association between vaccine and receipt of VA disability benefits for those without HFP (OR = 0.95, CI: 0.93, 0.97). Conclusions Risk of disability separation from the Army and receipt of disability compensation from the VA were not increased in association with prior exposure to AVA. This study provides evidence that vaccination against anthrax is not associated with long term disability. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect