Torsional motion of the left ventricle does not affect ventricular fluid dynamics of both foetal and adult hearts
| Autor: | Vivek Vasudevan, Choon Hwai Yap, Hadi Wiputra |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Swine 0206 medical engineering Myocardial Infarction Biomedical Engineering Biophysics 02 engineering and technology Wall shear Ventricular Function Left Motion 03 medical and health sciences Fetus 0302 clinical medicine Heart Rate Internal medicine Heart rate medicine Fluid dynamics Animals Humans Orthopedics and Sports Medicine Myocardial tissue Chemistry Rehabilitation Torsion (mechanics) Heart Stroke Volume Stroke volume Flow pattern Myocardial Contraction 020601 biomedical engineering medicine.anatomical_structure Ventricle Hydrodynamics Cardiology 030217 neurology & neurosurgery |
| Zdroj: | Journal of Biomechanics. 96:109357 |
| ISSN: | 0021-9290 |
| DOI: | 10.1016/j.jbiomech.2019.109357 |
| Popis: | Left ventricular torsion is caused by shortening and relaxation of the helical fibres in the myocardium, and is thought to be an optimal configuration for minimizing myocardial tissue strains. Characteristics of torsional motion has also been proposed to be markers for cardiac dysfunction. However, its effects on fluid and energy dynamics in the left ventricle have not been comprehensively investigated. To investigate this, we performed image-based flow simulations on five healthy adult porcine and two healthy human foetal left ventricles (representing two different length scales) at different degrees of torsional motions. In the adult porcine ventricles, cardiac features such as papillary muscles and mitral valves, and cardiac conditions such as myocardial infarctions, were also included to investigate the effect of twist. The results showed that, for all conditions investigated, ventricular torsional motion caused minimal changes to flow patterns, and consistently accounted for less than 2% of the energy losses, wall shear stresses, and ejection momentum energy. In contrast, physiological characteristics such as chamber size, stroke volume and heart rate had a much greater influence on flow patterns and energy dynamics. The results thus suggested that it might not be necessary to model the torsional motion to study the flow and energy dynamics in left ventricles. |
| Databáze: | OpenAIRE |
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