A CASE OF SUBCUTANEOUS PHAEOHYPHOMYCOSIS CAUSED BY EXSEROHILUM SPECIES IN AN IMMUNOCOMPROMISED PATIENT
| Autor: | Anaparthy Usharani, Ratna Harika Dusi, Nirupama Padmaja Bondili, Koppada Rajasekhar, Perala Balamurali Krishna |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Itraconazole Osteomyelitis Labia majora Exserohilum species lcsh:RL1-803 medicine.disease Keratitis subcutaneous nodules Phaeohyphomycosis medicine.anatomical_structure Subcutaneous nodule medicine lcsh:Dermatology Terbinafine Sinusitis business Meningitis medicine.drug |
| Zdroj: | Nasza Dermatologia Online, Vol 4, Iss 4, Pp 498-500 (2013) |
| ISSN: | 2081-9390 |
| Popis: | Phaeohyphomycoses are rare fungal infections, caused by dematiaceous fungi, manifested as cutaneous and subcutaneous infections, meningitis, sinusitis, keratitis, osteomyelitis and disseminated infection. This is a case report of a 45year old immuno compromised female on ART (Anti Retroviral therapy) presented with fever and generalized nodular lesions draining pus on face, hands, axilla, groin and labia majora since one month. Biopsy of the subcutaneous nodule on the lateral aspect of the thigh revealed septate fungal hyphae on 10% KOH (10% Potassium Hydroxide) mount. Fungal culture of the biopsy material on SDA (Sabouraud’s Dextrose Agar) at 25 0 C showed cotton wooly, dark gray to olivaceous black growth with black reverse and identified as dematiaceous fungi belonging to Exserohilum species by microscopy. The patient was put on Itraconazole 200mg BD in combination with Terbinafine 250mg BD for which she responded with healing of pustular lesions in two weeks and complete remission in two months. Key message: The increase in the fungal infections may be related to a heightened awareness of these infection in humans and improved diagnostic techniques. Inspite of availability of broad spectrum antifungal agents the fungal infections are causing disasters, it is imperative to investigate and pinpoint the causative agents in all infections to contribute data for further studies which will ultimately give an opportunity for better prevention and care. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|