PARENCHYMAL SPARING SURGERY IN PATIENTS WITH HEREDITARY RENAL CELL CARCINOMA: 10-YEAR EXPERIENCE
| Autor: | McClellan M. Walther, Allen Chernoff, Judi Herring, Erik Enquist, W. Marston Linehan, Peter L. Choyke |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Kidney
medicine.medical_specialty business.industry Urology medicine.medical_treatment Renal function Hereditary Papillary Renal Cell Carcinoma urologic and male genital diseases medicine.disease Nephrectomy Surgery Metastasis medicine.anatomical_structure medicine Carcinoma Von Hippel–Lindau disease business Kidney disease |
| Zdroj: | Journal of Urology. 165:777-781 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(05)66524-x |
| Popis: | Purpose: von Hippel-Lindau disease, hereditary papillary renal cell carcinoma, the Birt-Hogg-Dube syndrome and familial renal oncocytoma are familial renal tumor syndromes. These hereditary disorders are noteworthy for the development of multiple bilateral renal tumors and the risk of new tumors throughout life. One management strategy is observation of solid renal tumors until reaching 3 cm., then performing parenchymal sparing surgery. We present a 5-year update on our experience.Materials and Methods: From May 1988 to October 1998, 49 patients with hereditary renal cell carcinoma, including von Hippel-Lindau disease in 44, hereditary papillary renal cell carcinoma in 4 and the Birt-Hogg-Dube syndrome in 1, and 1 with familial renal oncocytoma underwent exploration to attempt renal parenchymal sparing surgery. Patients were followed prospectively with periodic screening for recurrence, metastasis and loss of renal function. Median followup was 79.5 months (range 0.7 to 205).Results: A total of 50 patien... |
| Databáze: | OpenAIRE |
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