Integrating surgery and genetic testing for the modern surgeon
| Autor: | Raul Caso, Alexander Lofthus, Michael Sosin, Matthew Beamer |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Genetic syndromes medicine.diagnostic_test business.industry Psychological intervention MEDLINE Review Article General Medicine medicine.disease Surgery 03 medical and health sciences 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis Intervention (counseling) Cancer genetics 030221 ophthalmology & optometry medicine business Disease manifestation Genetic testing |
| Zdroj: | Annals of Translational Medicine. 5:399-399 |
| ISSN: | 2305-5847 2305-5839 |
| Popis: | The field of cancer genetics is rapidly evolving and several genetic mutations have been identified in hereditary cancer syndromes. These mutations can be diagnosed via routine genetic testing allowing prompt intervention. This is especially true for certain variants of colorectal, breast, and thyroid cancers where genetic testing may guide surgical therapy. Ultimately, surgical intervention may drastically diminish disease manifestation or progression in individuals deemed as high-risk based on their genetic makeup. Understanding the concepts of gene-based testing and integrating into current surgical practice is crucial. This review addresses common genetic syndromes, tests, and interventions salient to the current surgeon. |
| Databáze: | OpenAIRE |
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