Feasibility and effectiveness of transcatheter aortic valve implantation in adults with congenital heart disease
| Autor: | Sundar Veerappan, Radwa Bedair, Michael Yeong, Mark Hamilton, Sarah Moharem-Elgamal, Mark Turner, Stephen Dorman, Massimo Caputo, Nathan E Manghat |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Heart disease Transcatheter aortic business.industry Aortic valve disease Population General Medicine Regurgitation (circulation) medicine.disease Transcatheter aortic valve replacement Nyha class Surgery Stenosis Bicuspid aortic valve RC666-701 medicine Diseases of the circulatory (Cardiovascular) system Adult congenital heart disease education business Hospital stay |
| Zdroj: | Moharem-Elgamal, S, Yeong, M, Veerappan, S, Manghat, N E, Bedair, R, Dorman, S, Caputo, M, Hamilton, M C K & Turner, M 2021, ' Feasibility and effectiveness of transcatheter aortic valve implantation in adults with congenital heart disease ', International Journal of Cardiology Congenital Heart Disease . https://doi.org/10.1016/j.ijcchd.2021.100116 International Journal of Cardiology Congenital Heart Disease, Vol 3, Iss, Pp 100116-(2021) |
| DOI: | 10.1016/j.ijcchd.2021.100116 |
| Popis: | AimThis study sought to evaluate the feasibility and effectiveness of TAVI for treatment of aortic stenosis in the ACHD population.Methods and resultsReview of 802 patients that underwent TAVI from January 2008 to November 2019. 13 ACHD patients with different underlying congenital anatomy were identified (isolated bicuspid aortic valve was excluded and not defined as ACHD). The main endpoints were: paravalvular aortic regurgitation> grade 2 post-procedure, and all-cause 30-day mortality. Periprocedural and post-procedural complications were defined according to the UK TAVI registry. Median age was 66.7 years (range 29–84 years). Eleven patients had severe aortic stenosis (AS), 1 had both severe AS and severe aortic regurgitation (AR) and 1 had severe AR. Median hospital stay was 9 days (range 6–28 days). One patient required a pacemaker post-TAVI. No mortality or paravalvular AR > grade 2 at 30-days. Twelve patients had a reduction in NYHA class on their first post TAVI follow-up.ConclusionTAVI is viable option as an alternative to surgery for ACHD patients. Further experience with the use of TAVI in the ACHD patients is required to assess long-term outcomes in this unique group of patients. |
| Databáze: | OpenAIRE |
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