Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation
| Autor: | Jonathan A. Ellman, Robert G. Bergman, Kateri A. Ahrendt |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
Mescaline Olefin fiber Tandem Stereochemistry Organic Chemistry Alkenes Biochemistry Catalysis Ruthenium chemistry.chemical_compound chemistry Cyclization Gallic Acid Yield (chemistry) medicine Physical and Theoretical Chemistry Methyl gallate Benzofuran Tricyclic medicine.drug |
| Zdroj: | Organic Letters. 5:1301-1303 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | [reaction: see text] A tetrahydrobis(benzofuran) mescaline analogue has been prepared in six steps and 38% overall yield from (4'-O-methyl)methyl gallate. The key step in this synthesis is a tandem cyclization reaction via directed C[bond]H activation followed by olefin insertion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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