Myocardial contraction fraction derived from cardiovascular magnetic resonance cine images-reference values and performance in patients with heart failure and left ventricular hypertrophy

Autor: Sebastian J. Buss, Marco Ochs, Matthias G Friedrich, Judith Paffhausen, Stefan Schönland, Nisha Arenja, Thomas A. Fritz, Fabian aus dem Siepen, Evangelos Giannitsis, Florian Andre, Arnt V. Kristen, Matthias Müller-Hennessen, Ute Hegenbart, Hugo A. Katus, Johannes Riffel
Rok vydání: 2016
Předmět:
Male
medicine.medical_specialty
Magnetic Resonance Imaging
Cine
030204 cardiovascular system & hematology
Left ventricular hypertrophy
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index
030218 nuclear medicine & medical imaging
Diagnosis
Differential
Hospitals
University
03 medical and health sciences
0302 clinical medicine
Sex Factors
Reference Values
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Retrospective Studies
Heart Failure
Ejection fraction
Chi-Square Distribution
medicine.diagnostic_test
business.industry
Hypertrophic cardiomyopathy
Age Factors
Magnetic resonance imaging
Stroke Volume
General Medicine
Stroke volume
Amyloidosis
medicine.disease
Prognosis
Myocardial Contraction
Hypertensive heart disease
Cardiac amyloidosis
ROC Curve
Heart failure
Area Under Curve
Case-Control Studies
Hypertension
Cardiology
Female
Hypertrophy
Left Ventricular
Cardiology and Cardiovascular Medicine
business
Zdroj: European heart journal. Cardiovascular Imaging. 18(12)
ISSN: 2047-2412
Popis: Aims Left ventricular hypertrophy (LVH) has strong prognostic implications and is associated with heart failure. Recently, myocardial contraction fraction (MCF) was identified as a useful marker for specifically identifying cardiac amyloidosis (CA). The purpose of this study was to evaluate the diagnostic accuracy of MCF for the discrimination of different forms of LVH. Methods and results We analysed cardiovascular magnetic resonance (CMR) scans of patients with CA (n = 132), hypertrophic cardiomyopathy (HCM, n = 60), hypertensive heart disease (HHD, n = 38) and in 100 age- and gender-matched healthy controls. MCF was calculated by dividing left ventricular (LV) stroke volume by LV myocardial volume. The diagnostic accuracy of MCF was compared to that of LV ejection fraction (EF) and the mass index (MI). Compared with controls (136.3 ± 24.4%, P
Databáze: OpenAIRE
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