Associations between antioxidant vitamins and the risk of invasive cervical cancer in Chinese women: A case-control study
Autor: | Chengjun Lin, Xiujuan Tian, Shiyu Han, Hong Zhu, Yumei Zhu, Liyuan Guo, Honghui Zhao, Dongwei Mao, Jianhua Che |
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Rok vydání: | 2015 |
Předmět: |
Adult
Vitamin China medicine.medical_specialty Adolescent Drug-Related Side Effects and Adverse Reactions medicine.medical_treatment Uterine Cervical Neoplasms Comorbidity Lower risk Risk Assessment Gastroenterology Antioxidants Article Young Adult chemistry.chemical_compound Internal medicine medicine Humans Neoplasm Invasiveness Young adult Aged Gynecology Cervical cancer Multidisciplinary business.industry Incidence Vitamin E Smoking Case-control study Vitamins Odds ratio Middle Aged medicine.disease chemistry Case-Control Studies Women's Health Female Risk assessment business |
Zdroj: | Scientific Reports |
ISSN: | 2045-2322 |
Popis: | Previous studies on the associations between dietary antioxidant vitamins and the risk of cervical cancer remain inconsistent and little evidence is available for serum antioxidant vitamins, which provide more accurate measurements of these nutrients. We conducted a case-control study of 458 incident cases with invasive cervical cancer and 742 controls to assess the effects of diet or serum antioxidant vitamins. Higher serum antioxidant vitamins were associated with a lower risk of cervical cancer after adjusting for potential confounders. The odds ratios (ORs) for the highest (vs. lowest) quartile were 0.66 (95% confidence interval [CI] = 0.46–0.93; P = 0.024) for α-carotene, 0.63 (95% CI = 0.45–0.90; P = 0.006) for β-carotene, 0.53 (95% CI = 0.37–0.74; P P |
Databáze: | OpenAIRE |
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