Neoplasia of the tubular genital tract in 42 goats
| Autor: | Darko Stefanovski, Meera C. Heller, Marie Eve Fecteau, Jennifer K. Linton, Susan J. Bender |
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| Rok vydání: | 2020 |
| Předmět: |
Leiomyosarcoma
medicine.medical_specialty 040301 veterinary sciences Population 0403 veterinary science Hospitals Animal Internal medicine Biopsy medicine Animals Clinical significance Genitalia education Retrospective Studies education.field_of_study General Veterinary medicine.diagnostic_test business.industry Medical record Goats 0402 animal and dairy science Retrospective cohort study 04 agricultural and veterinary sciences medicine.disease Prognosis 040201 dairy & animal science Leiomyoma Adenocarcinoma Female business |
| Zdroj: | Journal of the American Veterinary Medical Association. 256(7) |
| ISSN: | 1943-569X |
| Popis: | OBJECTIVE To assess the prevalence of tubular genital tract neoplasia in does evaluated at 2 veterinary teaching hospitals; describe the main clinical, surgical, and histopathologic or necropsy findings in affected does; and assess factors potentially associated with short-term prognosis in these animals. ANIMALS 42 does. PROCEDURES Medical records of 2 veterinary teaching hospitals were searched to identify does with neoplasia of the tubular genital tract. Signalment; history; physical and diagnostic imaging results; biopsy, surgery, and necropsy findings; and short-term outcome were recorded. Age and breed frequencies for the sample were compared with those of the overall hospital population, and variables of interest were tested for associations with a diagnosis of adenocarcinoma and with short-term outcome by statistical methods. RESULTS Median age at hospital admission (10 years) was greater for the study sample than for the general hospital population (2 years). Pygmy goats were overrepresented (22/42 [52%]). Common reasons for evaluation were bloody vaginal discharge or hematuria and abdominal straining. Adenocarcinoma (13/42 [31%]), leiomyoma (13 [31%]), and leiomyosarcoma (11 [26%]) were the most common tumors. Does with distant metastasis had greater odds of a diagnosis of adenocarcinoma (OR, 40.5) than does without distant metastasis. In the analysis adjusted for hemorrhagic discharge, odds of euthanasia for does with straining were 13 times those for does without straining. In the analysis adjusted for straining status, does with hemorrhagic discharge had almost 7 times the odds of euthanasia for does without this finding. The survival-to-discharge rate was low (13/42 [31%]). CONCLUSIONS AND CLINICAL RELEVANCE The frequency of adenocarcinomas in the study sample was unexpectedly high. Further research is needed to confirm the study findings. |
| Databáze: | OpenAIRE |
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