Effect of Transcranial Near-Infrared Light 1068 nm Upon Memory Performance in Aging Healthy Individuals: A Pilot Study
| Autor: | Paul L. Chazot, Gordon Dougal, Abdelkader Ennaceur |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Aging Infrared Rays Biomedical Engineering Pilot Projects Audiology Memory performance Placebo group Cognition Medicine Humans Radiology Nuclear Medicine and imaging Neuropsychological assessment Low-Level Light Therapy sub_healthsciences Near infrared light medicine.diagnostic_test sub_pharmacyandpharmacology business.industry Neuropsychology Middle Aged United States Full width at half maximum Healthy individuals sub_neuropsychology business sub_biomedicalsciences |
| Zdroj: | Photobiomodulation, photomedicine, and laser surgery. 39(10) |
| ISSN: | 2578-5478 1549-5418 |
| Popis: | Background: We present a pilot study of near-infrared (NIR) 1068 nm transcranial photobiomodulation therapy (PBM-T). Impact upon motor function, memory, and processing speed in healthy individuals, older than 45 years of age, was evaluated. Methods: PBM-T was performed at home using a transcranial phototherapy device, a helmet that comprised 14 air cooled light emitting diode panel arrays, with a peak wavelength of 1068 nm, full width at half maximum bandwidth of 60 nm and total average optical output power of 3.8 W. The device was used for 6 min twice daily on age-matched middle-aged subjects with normal intellectual function. The US Food and Drug Administration (FDA)-approved computerized assessment tool Automated Neuropsychological Assessment Metrics (ANAM) was adopted to quantify a series of cognitive and motor activities in the participating groups. Results: A significant improvement in motor function, memory performance, and processing speed was observed in healthy individuals with PBM-T compared to the placebo group. No adverse effects were reported. Conclusions: PBM-T may be a promising new approach to improve memory in healthy middle-aged individuals. ClinicalTrials.gov ID: NCT04568057. |
| Databáze: | OpenAIRE |
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