Chiral NADH model: design, synthesis, asymmetric reduction reaction, and fluorescence characteristics

Autor: Bo-Zhou Wang, Bao-Cai Xu, Nai-Xing Wang, Cui-Bing Bai, Lei-Yang Zhang, Zhan Yan, Yue-Hua Wu, Ning Liu, Vesna Tomasic
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: Abstract: A new type of NADH model compound, which has six asymmetric carbon centers, has been synthesized by an efficient and convenient method. We used NADH models combined with enzymes in the asymmetric reduction. It was the first time that dehydrogenase combined with NADH models instead of inorganic catalysts, such as MgCl2, was used in the asymmetric reduction. Furthermore, the experimental results showed that the new NADH model has the strongest fluorescence emission properties compared to previously reported models.
Databáze: OpenAIRE