Brain‐age estimation accuracy is significantly increased using multishell free‐water reconstruction
Autor: | Federico Nemmi, Mathilde Levardon, Patrice Péran |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Human Brain Mapping. 43:2365-2376 |
ISSN: | 1097-0193 1065-9471 |
Popis: | Although free-water diffusion reconstruction for diffusion-weighted imaging (DWI) data can be applied to both single-shell and multishell data, recent finding in synthetic data suggests that the free-water indices from single-shell acquisition should be interpreted with care, as they are heavily influenced by initialization parameters and cannot discriminate between free-water and mean diffusivity modifications. However, whether using a longer multishell acquisition protocol significantly improve reconstruction for real human MRI data is still an open question. In this study, we compare canonical diffusion tensor imaging (DTI), single-shell and multishell free-water imaging (FW) indices derived from a short, clinical compatible diffusion protocol (b = 500 s/mm |
Databáze: | OpenAIRE |
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