Brain‐age estimation accuracy is significantly increased using multishell free‐water reconstruction

Autor:	Federico Nemmi, Mathilde Levardon, Patrice Péran
Rok vydání:	2022
Předmět:	Aged 80 and over Male Diffusion Magnetic Resonance Imaging Diffusion Tensor Imaging Neurology Radiological and Ultrasound Technology Brain Humans Water Radiology Nuclear Medicine and imaging Neurology (clinical) Anatomy White Matter
Zdroj:	Human Brain Mapping. 43:2365-2376
ISSN:	1097-0193 1065-9471
Popis:	Although free-water diffusion reconstruction for diffusion-weighted imaging (DWI) data can be applied to both single-shell and multishell data, recent finding in synthetic data suggests that the free-water indices from single-shell acquisition should be interpreted with care, as they are heavily influenced by initialization parameters and cannot discriminate between free-water and mean diffusivity modifications. However, whether using a longer multishell acquisition protocol significantly improve reconstruction for real human MRI data is still an open question. In this study, we compare canonical diffusion tensor imaging (DTI), single-shell and multishell free-water imaging (FW) indices derived from a short, clinical compatible diffusion protocol (b = 500 s/mm
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ea7fe5ca6f50cacb7135c599b6d50d https://doi.org/10.1002/hbm.25792 Zobrazit plný text záznamu Plný text