Factors associated with poor outcomes in patients with lupus nephritis
| Autor: | A. Hurtado, Carlos Leon, B. Leclerq, C. De La Cuesta, C. Cely, F. Pachon, L. Garcia Mayol, E. Tozman, G. Barreto, A. Cepero, M. Esquenazi, Alfredo Valdés Paredes, J. C. Busse, A. Esquenazi, E. Borja, T. Khan, Gabriel Contreras, M. Almeida Suarez, N. Nahar, K. Iqbal, F. Ramirez-Seijas, Victoriano Pardo, H. Garcia Estrada, Arif Asif, D. Hoffman, Ivonne Hernandez Schulman, Oliver Lenz |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Mean arterial pressure Lupus nephritis 030204 cardiovascular system & hematology Hematocrit Gastroenterology White People 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Rheumatology Predictive Value of Tests Risk Factors Internal medicine medicine Humans Proportional Hazards Models 030203 arthritis & rheumatology Creatinine medicine.diagnostic_test Proportional hazards model business.industry Hazard ratio Case-control study Hispanic or Latino medicine.disease Lupus Nephritis Surgery Black or African American Elevated serum creatinine chemistry Case-Control Studies Kidney Failure Chronic Female business |
| Zdroj: | Lupus. 14:890-895 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1191/0961203305lu2238oa |
| Popis: | The objective of this study was to identify the factors associated with important clinical outcomes in a case-control study of 213 patients with lupus nephritis. Included were 47% Hispanics, 44% African Americans and 9% Caucasians with a mean age of 28 years. Fifty-four (25%) patients reached the primary composite outcome of doubling serum creatinine, end-stage renal disease or death during a mean follow-up of 37 months. Thirty-four percent African Americans, 20% Hispanics and 10% Caucasians reached the primary composite outcome ( P < 0.05). Patients reaching the composite outcome had predominantly proliferative lupus nephritis (WHO classes: 30% III, 32% IV, 18% V and 5% II, P < 0.025) with higher activity index score (7 ± 6 versus 5 ± 5, P |
| Databáze: | OpenAIRE |
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