Do the deceleration/acceleration capacities of heart rate reflect cardiac sympathetic or vagal activity? A model study
| Autor: | Guolong Cai, Luping Fang, Qing Pan, Ruofan Wang, Gangmin Ning, Jing Yan, Gongzhan Zhou |
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| Rok vydání: | 2015 |
| Předmět: |
Sympathetic Nervous System
Physiological significance Chemistry Model study Deceleration RR interval Acceleration Biomedical Engineering Models Cardiovascular Sympathetic activity Signal Processing Computer-Assisted Vagus Nerve 030204 cardiovascular system & hematology Computer Science Applications 03 medical and health sciences Autonomic nervous system Electrocardiography 0302 clinical medicine Heart Rate Heart rate Humans Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Medicalbiological engineeringcomputing. 54(12) |
| ISSN: | 1741-0444 |
| Popis: | Despite increased application of the deceleration capacity (DC) and acceleration capacity (AC) of heart rate indices as indicators of autonomic nervous system (ANS) function, it remains controversial as to whether they reflect cardiac sympathetic or vagal activity. We addressed this problem using a cardiovascular system model that allows analysis of DC and AC under controllable levels of sympathetic and vagal activities. Multi-scale DCs and ACs with various timescales T and wavelet scales s were computed from the simulated RR interval series under randomly fluctuating levels of ANS activity, and the correlations of the indices to ANS functions were assessed. Results showed that under the conventional scales (T = 1, s = 2), both DC and AC were solely dependent on vagal activity. With higher scales (T = 3, s = 5), both DC and AC were positively correlated to sympathetic activity and negatively correlated to vagal activity. These data suggest that DC and AC provide information on the same aspects of ANS activity and that their physiological significance is highly influenced by the timescales and wavelet scales used in the computation. |
| Databáze: | OpenAIRE |
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