Transcriptional response to hypoxia of normal and rheumatoid arthritis synovial fibroblasts
| Autor: | Elena Izquierdo, F Acquadro, Elena Gonzalo, José L. Pablos, Francisco J. Blanco, M J Del Rey, Alicia Usategui |
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| Jazyk: | angličtina |
| Předmět: |
musculoskeletal diseases
Medicine(all) Cell type Low oxygen business.industry Biochemistry Genetics and Molecular Biology(all) General Medicine Hypoxia (medical) medicine.disease General Biochemistry Genetics and Molecular Biology Rheumatoid arthritis Poster Presentation Gene expression Cancer research Medicine Transcriptional response Disease process medicine.symptom skin and connective tissue diseases business |
| Zdroj: | Journal of Translational Medicine |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/1479-5876-8-s1-p31 |
| Popis: | Rheumatoid arthritis (RA) synovium is characterized by very low oxygen concentrations but it is not clear how this factor contributes to the disease process. Hypoxia has profound and variable effects on gene expression in different cell types but these effects have not been systematically analysed in human fibroblasts. |
| Databáze: | OpenAIRE |
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