Comparison of the in vitro activity of levofloxacin and other antimicrobial agents against vancomycin-susceptible and vancomycin-resistant Enterococcus species
| Autor: | Marian Matushek, Gordon M. Trenholme, Mary K. Hayden |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Microbiology (medical)
Ofloxacin medicine.drug_class Antibiotics Levofloxacin Microbial Sensitivity Tests Penicillins medicine.disease_cause Microbiology Minimum inhibitory concentration Anti-Infective Agents Ciprofloxacin Vancomycin medicine heterocyclic compounds Vancomycin-resistant Enterococcus Antibacterial agent biology business.industry Drug Resistance Microbial General Medicine biochemical phenomena metabolism and nutrition bacterial infections and mycoses Antimicrobial biology.organism_classification Anti-Bacterial Agents Infectious Diseases Enterococcus bacteria Ampicillin business medicine.drug |
| Zdroj: | Diagnostic microbiology and infectious disease. 22(4) |
| ISSN: | 0732-8893 |
| Popis: | The in vitro activities of levofloxacin and other antibiotics against 133 clinical isolates of vancomycin-resistant and vancomycin-susceptible enterococci were evaluated. Only 14 (39%) of the vancomycin-susceptible isolates and 11 (11%) of the vancomycin-resistant isolates were susceptible to levofloxacin. Levofloxacin exhibited a marked inoculum effect for all enterococci tested. These results suggest that levofloxacin may be of limited use in the treatment of serious enterococcal infections. |
| Databáze: | OpenAIRE |
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