Effects of microwaves on membranes of hematopoietic cells in their structural and functional organization
| Autor: | Jitka Kautská, Dolores Rotkovská, Alena Bartoničková |
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| Rok vydání: | 1993 |
| Předmět: |
Male
Physiology Cell growth Cell Cell Membrane Biophysics Bone Marrow Cells General Medicine Biology In Vitro Techniques Transplantation Mice Membrane medicine.anatomical_structure Immunology medicine Animals Radiology Nuclear Medicine and imaging Interphase Irradiation Bone marrow Receptor Microwaves |
| Zdroj: | Bioelectromagnetics. 14(1) |
| ISSN: | 0197-8462 |
| Popis: | The role of cell membranes in stimulating and inhibiting the effects of microwaves was investigated in experiments carried out with a suspension of murine bone marrow cells irradiated with microwaves in vitro [f = 2.45 GHz, CW, specific absorption rate (SAR) = 12 W/kg]. Results obtained by means of a structural probe, 2.4-TNS, indicate that no structural changes occur in the region of the protein-lipid interphase under conditions of short-term irradiation with microwaves that induced temperatures in the range 36-45 degrees C (exposure time 315 and 525 s, respectively). Investigation of one functional parameter--the ability to produce hematopoietic colonies in the spleen after transplantation of the bone marrow irradiated in vitro by microwaves--indicated the possibility of affecting stimulatory and inhibitory effects of microwaves by using a blocker of cell receptors, Trimepranol. The role of microwaves as a physical factor interfering in the process of cell proliferation at the level of receptor regulation is discussed. |
| Databáze: | OpenAIRE |
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