Sixth nerve palsy in sporadic Burkitt Lymphoma
| Autor: | Andrew G. Lee, Bayan Al Othman, Ashwini Kini, Sowmya Yennam |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.medical_treatment Central nervous system Case Report Horizontal diplopia Sixth nerve palsy Metastasis lcsh:Ophthalmology immune system diseases hemic and lymphatic diseases medicine Diplopia Metastatic burkitt lymphoma Chemotherapy Base of skull business.industry Abdominal distension medicine.disease Lymphoma Ophthalmology medicine.anatomical_structure lcsh:RE1-994 medicine.symptom business Cavernous sinus syndrome |
| Zdroj: | American Journal of Ophthalmology Case Reports American Journal of Ophthalmology Case Reports, Vol 16, Iss, Pp-(2019) |
| ISSN: | 2451-9936 |
| Popis: | Purpose: To describe a unique presentation of Central Nervous System Burkitt Lymphoma. Observations: A 59-year-old male presented with new onset binocular horizontal diplopia five days after initial presentation with abdominal distension, weight loss, and night sweats. He was diagnosed with Burkitt Lymphoma with base of skull metastasis that was initially visible only on PET scan and subsequently resolved with chemotherapy. Conclusions and Importance: Burkitt Lymphoma (BL) is an aggressive type of B-cell, non-Hodgkin, lymphoma that arises due to a translocation of the MYC proto-oncogene. Although central nervous system (CNS) involvement has been described previously with BL, isolated sixth nerve palsy as the initial sign of CNS metastasis is rare. Suspicion should remain high for metastatic disease in patients presenting with acute-onset neurologic complaints even when initial imaging is negative as timely treatment can prevent poor outcomes. Keywords: Cavernous sinus syndrome, Sixth nerve palsy, Horizontal diplopia, Metastatic burkitt lymphoma |
| Databáze: | OpenAIRE |
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