Diagnostic yield of nondiagnostic thyroid nodules is not altered by timing of repeat biopsy
| Autor: | Carrie C. Lubitz, Anthony E. Samir, Douglas S. Ross, Gregory W. Randolph, Antonia E. Stephen, William C. Faquin, Giuseppe Barbesino, Sushruta S. Nagarkatti, Gilbert H. Daniels, Maria Hassan, Richard A. Hodin, Sareh Parangi, Randall D. Gaz |
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| Rok vydání: | 2012 |
| Předmět: |
Thyroid nodules
Male medicine.medical_specialty Time Factors Endocrinology Diabetes and Metabolism medicine.medical_treatment Biopsy Fine-Needle Thyroid Gland Thyrotropin Thyroiditis Cohort Studies Endocrinology medicine Humans Thyroid Nodule Aged Retrospective Studies Ultrasonography Gynecology medicine.diagnostic_test Radiotherapy business.industry Thyroid Thyroidectomy Retrospective cohort study Thyroid Cancer and Nodules Middle Aged medicine.disease Radiation therapy Fine-needle aspiration medicine.anatomical_structure Female Radiology business Cohort study |
| Zdroj: | Thyroid : official journal of the American Thyroid Association. 22(6) |
| ISSN: | 1557-9077 |
| Popis: | Guidelines from the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference recommend a repeat fine-needle aspiration biopsy (FNAB) after 3 months for thyroid nodules with a nondiagnostic (ND) result. Our aims were to assess which factors influenced their clinical management and to determine if the timing of the repeat FNAB affects the diagnostic yield.A retrospective institutional review of 298 patients from 1/2006 to 12/2007 with an ND FNAB was performed. The factors influencing the next step in management, including age, gender, history of radiation, presence of Hashimoto's thyroiditis, thyroid-stimulating hormone levels, and ultrasound characteristics, were evaluated. The effect of the time of the repeat FNABs on their diagnostic yield was assessed.Of the 298 patients in our cohort, 9% were referred directly for surgery, 76% had a repeat FNAB, and 15% were observed. Tumor size was the only independent variable correlated with treatment strategy after a ND FNAB. There was not a significant difference in diagnostic yields between repeat FNABs performed earlier than 3 months compared to those preformed later (p=0.58).The timing of repeat FNAB for an initial ND FNAB does not affect diagnostic yield of the repeat FNAB. |
| Databáze: | OpenAIRE |
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