Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression

Autor: Rima Habre, Kiros Berhane, Edward B. Rappaport, Yue Zhang, Theresa M. Bastain, William S. Linn, Muhammad T. Salam, Sandrah P. Eckel, Frank D. Gilliland
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
Health
Toxicology and Mutagenesis

Respiratory Tract Diseases
Nitric Oxide Synthase Type II
010501 environmental sciences
01 natural sciences
California
Epigenesis
Genetic

Exhaled nitric oxide
0302 clinical medicine
Haplotype
030212 general & internal medicine
Inducible nitric oxide synthase
Child
Air Pollutants
lcsh:Public aspects of medicine
Methylation
Environmental exposure
respiratory system
3. Good health
Exhalation
lcsh:Industrial medicine. Industrial hygiene
Biomarker (medicine)
Regression Analysis
Female
PM2.5
Biology
Nitric Oxide
complex mixtures
03 medical and health sciences
lcsh:RC963-969
medicine
Humans
Genetic Predisposition to Disease
Epigenetics
0105 earth and related environmental sciences
Asthma
Inflammation
Research
Public Health
Environmental and Occupational Health

lcsh:RA1-1270
Environmental Exposure
medicine.disease
respiratory tract diseases
13. Climate action
Immunology
Particulate Matter
Zdroj: Environmental Health
Environmental Health, Vol 16, Iss 1, Pp 1-10 (2017)
ISSN: 1476-069X
Popis: Background The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air pollutants. For example, susceptibility to airway inflammation from exposure to particulate matter with aerodynamic diameter
Databáze: OpenAIRE