Levels of circulating fibronectin receptor in adult and pediatric patients with human immunodeficiency virus type 1 infection
| Autor: | Donato Torre, G P Fiori, R Martegani, G Ferrario, Agostino Pugliese, C Zeroli, Issi M, Filippo Speranza, G Bonetta, M Giola |
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| Předmět: |
Microbiology (medical)
inorganic chemicals Adult Male Adolescent Clinical Biochemistry Immunology Human immunodeficiency virus (HIV) HIV Infections Biology medicine.disease_cause environment and public health Receptors Fibronectin Acquired immunodeficiency syndrome (AIDS) Fibronectin Receptor medicine Immunology and Allergy Humans Child Aids patients Acquired Immunodeficiency Syndrome Infant Middle Aged medicine.disease Virology Child Preschool HIV-1 bacteria Female Research Article |
| Zdroj: | Scopus-Elsevier |
| Popis: | We found a significant increase in fibronectin receptor (FNR) levels in the sera of adult human immunodeficiency virus type 1 (HIV-1)-infected patients, especially in those with AIDS (1,026.9 +/- 583.9 ng/ml; P < 0.0001). In contrast, AIDS patients with neurologic disorders and HIV-1-seropositive patients showed normal levels of FNR in serum. In addition, HIV-1-infected children showed increased levels of FNR in serum (824.4 +/- 333.5 ng/ml; P = 0.03). We suggest that an increase of FNR levels in AIDS patients is related to enhanced expression of FNR on HIV-1-infected cells. |
| Databáze: | OpenAIRE |
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