Desogestrel versus antagonist injections for LH suppression in oocyte donation cycles: a crossover study
| Autor: | Francisca Martínez, Jorge Rodriguez-Purata, Dalia Beatriz Rodríguez, Buenaventura Coroleu, Elisabet Clua, Ignacio Rodríguez |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Gonadotropin-Releasing Hormone Young Adult 03 medical and health sciences Hormone Antagonists 0302 clinical medicine Endocrinology Ovulation Induction Pregnancy Desogestrel Block (telecommunications) Internal medicine Humans Medicine Retrospective Studies Cross-Over Studies 030219 obstetrics & reproductive medicine Oocyte Donation business.industry Antagonist Obstetrics and Gynecology Luteinizing Hormone Oocyte Crossover study medicine.anatomical_structure Oocyte donation Female Follicle Stimulating Hormone Human business Luteinizing hormone medicine.drug |
| Zdroj: | Gynecological Endocrinology. 35:878-883 |
| ISSN: | 1473-0766 0951-3590 |
| DOI: | 10.1080/09513590.2019.1604661 |
| Popis: | To study whether ovarian response to corifollitropin among oocyte donors (OD) is different when oral desogestrel (DSG) is used to block the luteinizing hormone (LH) surge when compared to GnRH-antagonist use. This is a retrospective, cohort study at a private, university-based, IVF center including 35 OD. Patients underwent two stimulation cycles under corifollitropin alfa (CFT), one under an antagonist and another under DSG, between February 2015 and May 2017. In antagonist cycles, daily ganirelix was administered since a leading follicle reached 14 mm. In the DSG cycles, daily oral DSG was prescribed. The main outcome measure was oocytes retrieved. Compared to antagonist cycles, cycles under DSG received fewer injections (10.3 ± 2.8 |
| Databáze: | OpenAIRE |
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