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Iris cysts in horses are often asymptomatic and noticed incidentally. However, cysts can cause local corneal oedema and erratic behaviour like shying, decreased performance and head-shaking.To describe the use of diode laser as a noninvasive treatment option for iris cysts in the horse and to document factors influencing its efficacy, associated complications, long-term outcome and rate of recurrence.Retrospective case series.Case records of horses treated for iris cysts by diode laser at the Utrecht University Equine Clinic were reviewed between 2008 and 2020. Diagnosis was based on ophthalmic and ultrasonographic evaluation. Long-term follow-up was obtained in two phases, a telephone survey with the owner and a photographic re-evaluation of the treated eyes.Thirty-five horses were included, with a total of 46 eyes treated. One day after diode laser treatment (short-term), 35/46 treated eyes had a good decrease in cyst size, 7/46 had a moderate effect, 1/46 had a minimal effect, 1/46 had no effect, and in two cases the effect was unspecified. The decrease in size after diode laser treatment in polycystic eyes (odds ratio [OR] 0.381, 95% CI 0.1530-0.724), p = 0.001), thick-walled cysts (OR = 0.139; CI = 0.023-0.726, p = 0.02) and hyperplastic corpora nigra (OR = 0.081; CI = 0.004-0.528, p = 0.03) was significantly less satisfactory, with ORs of 0.381, 0.139 and 0.081, respectively. Minor complications, such as mild reactive uveitis, were reported in 8/46 (17%) eyes. On long-term follow-up (median 19 months; IQR 25.5), clinical signs had diminished or disappeared in most cases (93%) and 83% of the owners would recommend the treatment. Based on long-term photographic re-evaluation (median 32.5 months; IQR 49.75), 2/16 cases of recurrence were seen.Retrospective design, follow-up by telephone questionnaire and photographic re-evaluation. Loss to follow-up in the photographic re-evaluation.Both short- and long-term results indicate diode laser treatment is a useful and safe option for iris cyst size reduction, with a low risk of recurrence. Presurgical ultrasonography is recommended to assess the feasibility of treatment and to allow for better surgical planning.背景:马虹膜囊肿通常是无症状，偶然发现的。然而，囊肿可引起局部角膜水肿以及马匹不稳定的行为，如害羞、表现下降和甩/摇头等。 目的:描述使用半导体激光作为马虹膜囊肿的非侵入性治疗方案，并记录影响其疗效、相关并发症、长期结果和复发率的因素。 研究设计:回顾性病例系列研究 方法:回顾了2008年至2020年在乌特勒支大学马诊所使用二极管激光治疗马虹膜囊肿的病例记录。诊断基于眼科和超声检查进行评估。长期随访分两个阶段进行，一是与患者电话调查，二是对被治疗的眼睛进行照片重新评估。 结果:记录的35匹马，共治疗46只眼睛。在经过二极管激光治疗后1天(短期)显示，35例(35/46)囊肿明显减小，7例效果中等，1例效果轻微，1例无效果，2例效果不明。经二极管激光治疗后，囊肿缩小数据显示，有多囊性眼(OR= 0.381；CI =0.153-0.724，p= 0.001)、厚壁性眼(OR = 0.139；CI = 0.023 - 0.726, p =0.02)和增殖性黑体(OR = 0.081; CI = 0.004 - 0.528, p=0.03)的患马，效果不佳，优势比OR分别为0.381、0.139和0.081。记录中另有8只眼有轻微并发症，如轻度反应性葡萄膜炎(8/46,17%)。长期随访(中位数19个月；IQR 25.5)，绝大多数临床症状减轻或消失(93%)；83%的马主会建议治疗。根据眼部照片进行长期再评价(中位数32.5个月；IQR 49.75)，有 2例(2/16)复发。 主要局限性:本研究属于回顾性质，通过电话问卷和摄影照片进行重新评估。基于照片的重估失去了一些随访数据。 结论:短期和长期结果表明，二极管激光治疗马虹膜囊肿是一种有效和安全的选择，复发风险低。建议术前超声检查以评估治疗的可行性，并制定更好的手术计划. |
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