Annuloaortic ectasia and giant cell arteritis
| Autor: | Franca Gori, Chiara Anichini, Gabriella Nesi, Gian Franco Gensini, Carlo Sorbara, Pierluigi Stefàno, Stefano Romagnoli, Sandro Gelsomino |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Aortic Valve Insufficiency Giant Cell Arteritis Thoracic aortic aneurysm Aortic aneurysm Aortic valve replacement Ectasia medicine.artery Ascending aorta medicine Humans Aortic valve regurgitation Aged Retrospective Studies Aortic dissection Aged 80 and over Aortic Aneurysm Thoracic business.industry Cardiovascular Surgical Procedures Annuloaortic ectasia medicine.disease Surgery cardiovascular system Female medicine.symptom Cardiology and Cardiovascular Medicine business Dilatation Pathologic |
| Zdroj: | The Annals of thoracic surgery. 80(1) |
| ISSN: | 1552-6259 |
| Popis: | Background Thoracic aortic aneurysm, aortic dissection and aortic valve regurgitation have been widely described in patients with Horton disease, also known as giant cell arteritis. We present our midterm experience with patients with these features. Methods A total of 386 cases of ascending aorta and aortic valve replacement performed for thoracic aortic aneurysm and aortic insufficiency between 1998 and 2004 were reviewed. Among them 10 cases of histopathologically confirmed GAA were identified. Patients were predominantly female (90%); the mean age was 74.5 ± 4.6 years. Results Eight patients (80%) showed typical annuloaortic ectasia, leading to significant aortic valve regurgitation. These subjects underwent a Bentall operation. Two patients whose sinuses seemed undilated and macroscopically normal had separate valve graft replacement at first operation and underwent reoperation due to dilatation of the native sinuses. Eight patients had partial aortic arch replacement (hemiarch), and 1 underwent total arch replacement. Six-year survival was 0.9 ± 0.09; freedom from reoperation at 6 years was 0.77 ± 0.13. Conclusions Annuloaortic ectasia is a common finding in giant cell arteritis. In patients with Horton disease, the aortic root should always be replaced regardless of macroscopic findings. |
| Databáze: | OpenAIRE |
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