Incidence and risk factors for pneumomediastinum in COVID-19 patients in the intensive care unit
| Autor: | Servet Özdemir, Necati Çitak, Deniz Özel Bilgi, Gülsüm Oya Hergünsel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty medicine.medical_treatment Thoracic Pneumomediastinum Peak inspiratory pressure law.invention law Risk Factors Internal medicine medicine Humans Intensive care unit Tidal volume Mediastinal Emphysema Retrospective Studies Mechanical ventilation business.industry AcademicSubjects/MED00920 SARS-CoV-2 Incidence (epidemiology) Incidence COVID-19 Odds ratio Original Articles medicine.disease Prognosis Severe acute respiratory syndrome coronavirus-2 Respiration Artificial Confidence interval Intensive Care Units Cardiology Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | Interactive Cardiovascular and Thoracic Surgery |
| ISSN: | 1569-9285 1569-9293 |
| Popis: | OBJECTIVES The incidence of pneumomediastinum (PNMD), its causes of development and its effect on prognosis in the coronavirus disease 2019 (COVID-19) are not clear. METHODS Between March 2020 and December 2020, 427 patients with real-time reverse transcriptase-polymerase chain reaction-confirmed COVID-19 admitted to the intensive care unit were analysed retrospectively. Using receiver operating characteristic analysis, the area under the curve (AUC) for initial invasive mechanical ventilation (MV) variables such as initial peak inspiratory pressure (PIP), PaO2/FiO2 (P/F ratio), tidal volume, compliance and positive end-expiratory pressure was evaluated regarding PNMD development. RESULTS The incidence of PNMD was 5.6% (n = 24). PNMD development rate was 2.7% in non-invasive MV and 6.2% in MV [odds ratio (OR) 2.352, 95% confidence interval (CI) 0.541–10.232; P = 0.400]. In the multivariate analysis, the independent risk factors affecting the development of PNMD were PIP (OR 1.238, 95% CI 1.091–1.378; P Severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus disease 2019 (COVID-19), is associated with considerable morbidity and mortality [1]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|