A case of Graves' disease associated with Klinefelter's syndrome
| Autor: | Motohisa Nagamine, Shu-ichi Yamashita, Shigeru Matsukura, Tadanobu Kuribayashi |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Exophthalmos Graves' disease Disease Gastroenterology Gonadotropin-Releasing Hormone Klinefelter Syndrome Weight loss Internal medicine medicine Humans Thyrotropin-Releasing Hormone X chromosome business.industry Karyotype Atrial fibrillation General Medicine medicine.disease Graves Disease Thyroxine Endocrinology Gynecomastia Karyotyping Triiodothyronine medicine.symptom business |
| Zdroj: | Japanese Journal of Medicine. 29:523-526 |
| ISSN: | 1881-123X 0021-5120 |
| Popis: | Graves' disease was found in a 41-year-old, married male patient with Klinefelter's syndrome. The patient began having finger tremor 5 years previously, and developed palpitation and weight loss 3 months prior to examination. He had a diffuse goiter, exophthalmos, and atrial fibrillation. Plasma levels of T3, T4 and free T4 were 2.8 ng/ml, 16.6 micrograms/dl and 4.5 ng/dl respectively. [123I] uptake was 53%, and TSH receptor antibody was 75%. Although he had no gynecomastia, his general physical appearance was that of typical eunuchoism. Chromosome studies showed a karyotype of 47,XXY. A diagnosis of Graves' disease associated with Klinefelter's syndrome was made. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|