Tobacco smoking and risk of endometriosis: a systematic review and meta-analysis
| Autor: | Elena Ricci, Sonia Cipriani, Vito Chiantera, Francesca Bravi, Francesca Chiaffarino, Fabio Parazzini, Paola Viganò, Carlo La Vecchia |
|---|---|
| Přispěvatelé: | Bravi, F., Parazzini, F., Cipriani, S., Chiaffarino, F., Ricci, E., Chiantera, V., Viganò, P., La Vecchia, C. |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Endometriosis MEDLINE Global Health Risk Factors Internal medicine Epidemiology Obstetrics and Gynaecology medicine EPIDEMIOLOGY Humans Gynecology business.industry Risk Factor Research Smoking General Medicine GYNAECOLOGY Former Smoker medicine.disease Settore MED/40 - Ginecologia E Ostetricia Relative risk Meta-analysis Smoking cessation Female Smoking Cessation Morbidity business Cohort study Human |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | Objective Since conflicting results have been published on the role of tobacco smoking on the risk of endometriosis, we provide an up-to-date summary quantification of this potential association. Design We performed a PubMed/MEDLINE search of the relevant publications up to September 2014, considering studies on humans published in English. We searched the reference list of the identified papers to find other relevant publications. Case–control as well as cohort studies have been included reporting risk estimates on the association between tobacco smoking and endometriosis. 38 of the 1758 screened papers met the inclusion criteria. The selected studies included a total of 13 129 women diagnosed with endometriosis. Setting Academic hospitals. Main outcome measure Risk of endometriosis in tobacco smokers. Results We obtained the summary estimates of the relative risk (RR) using the random effect model, and assessed the heterogeneity among studies using the χ 2 test and quantified it using the I 2 statistic. As compared to never-smokers, the summary RR were 0.96 (95% CI 0.86 to 1.08) for ever smokers, 0.95 (95% CI 0.81 to 1.11) for former smokers, 0.92 (95% CI 0.82 to 1.04) for current smokers, 0.87 (95% CI 0.70 to 1.07) for moderate smokers and 0.93 (95% CI 0.69 to 1.26) for heavy smokers. Conclusions The present meta-analysis provided no evidence for an association between tobacco smoking and the risk of endometriosis. The results were consistent considering ever, former, current, moderate and heavy smokers, and across type of endometriosis and study design. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|