Propionic acid production in an in situ cell retention bioreactor
| Autor: | Ashok K. Srivastava, Vandana Goswami |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
In situ
Chromatography biology Chemistry Propionibacterium Cell Propionibacterium acidipropionici General Medicine Spin filter biology.organism_classification Applied Microbiology and Biotechnology Acid production Culture Media Dilution Bioreactors medicine.anatomical_structure Fermentation Bioreactor medicine Propionates Filtration Bacteria Biotechnology |
| Zdroj: | Applied Microbiology and Biotechnology. 56:676-680 |
| ISSN: | 1432-0614 0175-7598 |
| DOI: | 10.1007/s002530000582 |
| Popis: | Continuous fermentations were conducted with in situ cell retention using spin filters (pore size 5 microm and 10 microm) for propionic acid production by Propionibacterium acidipropionici. Continuous fermentation with a 5-microm pore size spin filter resulted in 50% cell retention. Propionic acid productivity was enhanced (0.9 g l(-1) h(-1)) by approximately four-fold compared to conventional batch fermentation (0.25 g l(-1) h(-1)). The in situ cell retention (5-microm pore size spin filter) bioreactor was operated continuously and smoothly for 8 days at a dilution rate of D=0.05 h(-1). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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