Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation
Autor: | Viviana Teresa Orlandi, Nicola Trivellin, Francesco Onelia, Alberto Pizzolato, Gaudenzio Meneghesso, Enrico Zanoni, Claudia Del Vecchio, Marco Barbato, Fabrizio Dughiero, Matteo Meneghini, Andrea Crisanti, Matteo Buffolo |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Technology
2019-20 coronavirus outbreak Materials science Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 LED SARS-CoV-2 UVC disinfection inactivation virucide 01 natural sciences Article law.invention 03 medical and health sciences 0302 clinical medicine law 0103 physical sciences General Materials Science 030212 general & internal medicine Irradiation 010302 applied physics Microscopy QC120-168.85 business.industry QH201-278.5 fungi Engineering (General). Civil engineering (General) TK1-9971 Descriptive and experimental mechanics Optoelectronics Electrical engineering. Electronics. Nuclear engineering TA1-2040 business Light-emitting diode |
Zdroj: | Materials; Volume 14; Issue 9; Pages: 2315 Materials, Vol 14, Iss 2315, p 2315 (2021) Materials |
ISSN: | 1996-1944 |
DOI: | 10.3390/ma14092315 |
Popis: | We report on the design, characterization and validation of a spherical irradiation system for inactivating SARS-CoV-2, based on UV-C 275 nm LEDs. The system is designed to maximize irradiation intensity and uniformity and can be used for irradiating a volume of 18 L. To this aim: (i) several commercially available LEDs have been acquired and analyzed; (ii) a complete optical study has been carried out in order to optimize the efficacy of the system; (iii) the resulting prototype has been characterized optically and tested for the inactivation of SARS-CoV-2 for different exposure times, doses and surface types; (iv) the result achieved and the efficacy of the prototype have been compared with similar devices based on different technologies. Results indicate that a 99.9% inactivation can be reached after 1 min of treatment with a dose of 83.1 J/m2. |
Databáze: | OpenAIRE |
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