Guideline adherence and long-term clinical outcomes in patients with acute myocardial infarction: a Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) substudy
| Autor: | Hideki Wada, Manabu Ogita, Satoru Suwa, Koichi Nakao, Yukio Ozaki, Kazuo Kimura, Junya Ako, Teruo Noguchi, Satoshi Yasuda, Kazuteru Fujimoto, Yasuharu Nakama, Takashi Morita, Wataru Shimizu, Yoshihiko Saito, Atsushi Hirohata, Yasuhiro Morita, Teruo Inoue, Atsunori Okamura, Toshiaki Mano, Kazuhito Hirata, Kengo Tanabe, Yoshisato Shibata, Mafumi Owa, Kenichi Tsujita, Hiroshi Funayama, Nobuaki Kokubu, Ken Kozuma, Shiro Uemura, Tetsuya Toubaru, Keijiro Saku, Shigeru Oshima, Kunihiro Nishimura, Yoshihiro Miyamoto, Hisao Ogawa, Masaharu Ishihara, Tadaya Sato, Hiroyuki Kyono, Tetsuya Tobaru, Takahito Sone, Yasuhiro Sone, Masashi Fujino, Kunihiko Nishimura, Junichi Kotani, Hiroyuki Okura, Masaaki Uematsu, Shirou Uemura, Seiji Hokimoto |
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| Rok vydání: | 2020 |
| Předmět: |
Cardiovascular event
Male medicine.medical_specialty Time Factors medicine.medical_treatment Treatment outcome Adrenergic beta-Antagonists Myocardial Infarction 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine Revascularization Coronary Angiography 03 medical and health sciences Electrocardiography 0302 clinical medicine Japan Internal medicine medicine Humans In patient 030212 general & internal medicine Myocardial infarction Hospital Mortality Prospective Studies Registries Aged Aged 80 and over Angiotensin Receptor Antagonists Aspirin business.industry Guideline adherence General Medicine Middle Aged medicine.disease Prognosis Clinical Practice Survival Rate Female Guideline Adherence Hydroxymethylglutaryl-CoA Reductase Inhibitors Morbidity Cardiology and Cardiovascular Medicine business Platelet Aggregation Inhibitors Follow-Up Studies |
| Zdroj: | European heart journal. Acute cardiovascular care. 9(8) |
| ISSN: | 2048-8734 |
| Popis: | Background: The association between guideline adherence and long-term outcomes in patients with acute myocardial infarction in real-world clinical practice remains unclear. Methods: We investigated 3283 consecutive patients with acute myocardial infarction who were selected from a prospective, nation-wide, multicentre registry (J-MINUET) database covering 28 institutions in Japan between July 2012 and March 2014. Among the 2757 eligible patients, we evaluated the use of seven guideline-recommended therapies, including urgent revascularisation, door-to-balloon time of 90 minutes or less, and five discharge medications (P2Y12 inhibitors on aspirin, beta-blockers, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, statins, lipid-lowering drugs). The primary endpoint was a composite of all-cause death, non-fatal myocardial infarction, non-fatal stroke, cardiac failure and urgent revascularisation for unstable angina up to 3 years. Results: The overall median composite guideline adherence was 85.7%. Patients were divided into the following three groups: complete (100%) adherence group (n=862); moderate adherence (75% to Conclusion: The use of guideline-based therapies for patients with acute myocardial infarction in contemporary clinical practice was associated with significant decreases in adverse long-term clinical outcomes. Trial registration: UMIN Unique trial Number: UMIN000010037 |
| Databáze: | OpenAIRE |
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