Enzyme immobilization on heparin
| Autor: | V.N. Smirnov, Z. A. Streltsova, Chazov Ei, Il'ina Ev, Vladimir P. Torchilin |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
chemistry.chemical_classification
Immobilized enzyme Heparin Chemistry Biomedical Engineering Enzymes Immobilized Combinatorial chemistry Enzyme Activation Biomaterials chemistry.chemical_compound Enzyme Biochemistry Ethyldimethylaminopropyl Carbodiimide medicine Chymotrypsin Macromolecule medicine.drug Carbodiimide |
| Zdroj: | Journal of Biomedical Materials Research. 12:585-590 |
| ISSN: | 1097-4636 0021-9304 |
| Popis: | We describe the preparation and some of the properties of heparin-bound alpha-chymotrypsin that were obtained via activation of heparin with water-soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low-molecular- weight and macromolecular substrates. The heparin-bound enzymes could have a wide range of medical applications. |
| Databáze: | OpenAIRE |
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