Botulinum toxin-treatment of localized provoked vulvodynia refractory to conventional treatment
| Autor: | Thomas Hedebo Hansen, Mette Meinert, Rikke Guldberg |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty NRS Vulvodynia Botulinum toxins Electromyography Injections Intramuscular Type A law.invention 03 medical and health sciences Pelvic pain 0302 clinical medicine Quality of life Randomized controlled trial Refractory law Surveys and Questionnaires Internal medicine medicine Humans 030212 general & internal medicine Botulinum Toxins Type A Pain Measurement 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics and Gynecology medicine.disease Botulinum toxin Treatment Outcome Dyspareunia Neuromuscular Agents Reproductive Medicine Quality of Life Female Cotton swab medicine.symptom business Sexuality Follow-Up Studies medicine.drug |
| Zdroj: | Hedebo Hansen, T, Guldberg, R & Meinert, M 2019, ' Botulinum toxin-treatment of localized provoked vulvodynia refractory to conventional treatment ', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 234, no. March, pp. 6-9 . https://doi.org/10.1016/j.ejogrb.2018.12.013 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/j.ejogrb.2018.12.013 |
| Popis: | INTRODUCTION: We wanted to evaluate the efficacy of botulinum toxin type A (botulinum toxin) treatment on vulvodynia refractory to conventional treatment.MATERIAL AND METHODS: A follow-up study on botulinum toxin treatment was conducted at Aarhus University Hospital (n = 109). Seventy-nine completed the follow-up. The women included had localized provoked vulvodynia, refractory to first line treatment and were treated with 100*I.E. botulinum toxin electromyography (EMG) guided in the musculus levator ani in the period from March 2012 to May 2015(1). The outcome measures were: Dyspareunia, Negative Interference in Quality of Life (NIQL) and cotton swab test all rated on the numerical rating scale (NRS) and active vitae sexualis. Follow-up was conducted at six months.RESULTS: The women experienced significant improvements on, dyspareunia, which decreased to 5.82 from 7.82 (p CONCLUSION: Women injected with 100*I.E. botulinum toxin EMG guided, diagnosed with localized provoked vulvodynia refractory to conventional non invasive treatment, had a reduction in dyspareunia and improved quality of life. Injection of botulinum toxin had no significant effect on vitae sexualis. Randomized controlled trials are, however, much needed. |
| Databáze: | OpenAIRE |
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