Cognitive improvement after carotid artery stenting in patients with symptomatic internal carotid artery near-occlusion
| Autor: | Jian Zhang, Li Po Song, Wei Wei Zhang, Xunming Ji, Yong Quan Gu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Carotid arteries Neuropsychological Tests 03 medical and health sciences 0302 clinical medicine Cognition medicine.artery Internal medicine Occlusion Medicine Humans In patient Carotid Stenosis Cognitive Dysfunction 030212 general & internal medicine Stroke Aged business.industry Incidence (epidemiology) Endovascular Procedures Montreal Cognitive Assessment medicine.disease Treatment Outcome Neurology Cardiology Female Stents Neurology (clinical) Internal carotid artery business 030217 neurology & neurosurgery Carotid Artery Internal |
| Zdroj: | Journal of the neurological sciences. 404 |
| ISSN: | 1878-5883 |
| Popis: | To investigate the influence of carotid artery stenting (CAS) with embolic protection device (EPD) on the cognitive function of patients with near-occlusion of the cervical internal carotid artery (ICA).From February 2014 to December 2017, a total of 79 symptomatic patients were recruited in this study. Of these patients, 31 patients refused to receive CAS therapy. They were divided into the CAS group (48 patients) and the medical treatment group (31 patients). Montreal cognitive assessment (MoCA) instrument was used for the evaluation of cognitive function. The analyzed endpoints included cumulative 12 month incidence of ipsilateral ischemic cerebrovascular events and MoCA scores at 1 month and 12 months after treatment.Cumulative 12 months incidence of ipsilateral ischemic cerebrovascular events was lower in patients who underwent CAS than in patients on medical treatment (P 0.05). In CAS group, the total MoCA score, scores of attention and delayed recall at months 1 and 12 increased when compared with those at baseline (P 0.05). In medical treatment group, the total MoCA score and attention score at month 12 decreased when compared with those at baseline (P 0.05). In CAS group, the total MoCA score, scores of line connection test, drawing clock, attention and delayed recall were improved at 1 and 12 months when compared with medical treatment at the same time points (P 0.05).CAS with EPD not only decreases the risk of ipsilateral TIA and stroke but also may improve the cognitive function of symptomatic patients with ICA near-occlusion. |
| Databáze: | OpenAIRE |
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