Recovery of Lymphocyte CD4+: CD8+ Ratio in Patients Treated with Lysozyme
| Autor: | Gianni Sava, F. Cartel, Sabrina Pacor, V. Ceschia, G. Cartei |
|---|---|
| Přispěvatelé: | Cartei, F., Cartei, G., Ceschia, V., Pacor, Sabrina, Sava, Gianni |
| Rok vydání: | 1992 |
| Předmět: |
cancer patient
medicine.medical_specialty medicine.medical_treatment Lymphocyte Lysozyme CD4-CD8 Ratio Gastroenterology Helper/suppressor lymphocytes chemistry.chemical_compound Pharmacotherapy cancer patients Therapy Internal medicine medicine Pharmacology (medical) Chemotherapy business.industry Cancer General Medicine medicine.disease Clinical trial medicine.anatomical_structure chemistry Immunology business CD8 |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1179-1918 0114-2402 |
| Popis: | A group of 23 patients, affected by malignant diseases (n = 21) or suffering from inflammatory diseases (n = 2) and characterised by a general reduction in total lymphocytes and an altered CD4+: CD8+ ratio (mainly low), were enrolled in a phase II clinical trial studying the effect of oral treatment with lysozyme chloride. The cancer patients were mainly in complete remission (19 of 21) after anticancer treatment, but 2 had drug unmaintained stable minimal disease. Lysozyme treatment, 2 g/day for periods up to longer than 90 days, was started after a washout period of at least 60 days after chemotherapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink