Uptake of proline by brushborder vesicles isolated from human kidney cortex

Autor:	John W. Foreman, Stanton Segal, Louise M. Pepe, Kristina Ginkinger, Pamela D. McNamara
Rok vydání:	1985
Předmět:	Alanine Kidney Cortex Microvilli Proline Vesicle Glycine Rat kidney Human kidney Biology In Vitro Techniques Biochemistry Cortex (botany) Kidney Tubules Proximal Hydroxyproline Kinetics Membrane Proline transport Humans
Zdroj:	Biochemical medicine. 34(3)
ISSN:	0006-2944
Popis:	Proline transport into renal brushborder membrane vesicles isolated from human kidney is mediated by two uptake systems. The high-affinity system is stimulated by a Na gradient and appears to be shared with glycine while the low-affinity system is not. Uptake curves of low concentrations of proline exhibit a Nagradient-dependent overshoot indicative of electrogenic transport. The proline transport systems observed in isolated human renal brushborder membrane vesicles appear to have characteristics similar to those in rat kidney membranes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4054d285440756eabba8c59c924f278f https://pubmed.ncbi.nlm.nih.gov/4096719 Zobrazit plný text záznamu