Imported malaria in metropolitan France, from recommendations to clinical practice - proposal for improvement
| Autor: | A. Dupré, Sandrine Houzé, C. Choquet, Sophie Matheron, A. Bleibtreu, N. Argy, A. Leleu |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Antimalarials parasitic diseases medicine Humans Imported malaria Retrospective Studies Travel biology business.industry Plasmodium falciparum Emergency department biology.organism_classification Malaria Metropolitan France Clinical Practice Infectious Diseases Infectious disease (medical specialty) Vomiting Chills France medicine.symptom business |
| Zdroj: | Infectious diseases now. 51(8) |
| ISSN: | 2666-9919 |
| Popis: | Background Approximately 5000 cases of imported malaria are observed each year in metropolitan France. Guidelines for the prevention and management of imported malaria were published by the French infectious disease society (French acronym SPILF) in 2017. Objective Study objective was to describe in a retrospective analysis (2015–2016) imported malaria cases recorded in a Parisian hospital, to analyze the congruence to previous guidelines (2014), deviation in respect to post hoc published guidelines and potential areas for improvement. Results Two hundred and one cases were analyzed using medical charts. There was a majority of men (sex ratio 2/1), with a mean age of 43 years at diagnosis. The main area of infection acquisition was sub-Saharan Africa (97%). The average time since return from the endemic area was 20 days. Patients consulted the emergency department for flu-like syndrome (32%), fever or chills (28%), and gastrointestinal symptoms (22%). Blood smears mainly identified Plasmodium falciparum (n = 180, 90%). There were 52 (26%) severe malaria episodes. Conclusion The analysis of national guideline adequacy highlighted difficulties in obtaining a complete biological workup at baseline, managing patients with vomiting, and in the post-treatment follow-up. |
| Databáze: | OpenAIRE |
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