Risk factors of local recurrence following implant-based breast reconstruction in breast cancer patients
| Autor: | Yukiko Kajiwara, Kensuke Kawasaki, Mitsuya Ito, Hiroya Mihara, Takanori Kin, Miwa Fujihara, Reina Maeda, Shoichiro Ohtani, Kouichi Ichimura, Ayako Ueno, Naritaka Kimura, Tadahiko Shien, Rie Yamasaki |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Mammaplasty medicine.medical_treatment Reproductive medicine Breast Neoplasms 030230 surgery lcsh:Gynecology and obstetrics Systemic therapy 03 medical and health sciences Breast cancer 0302 clinical medicine Local recurrence medicine Lymphatic vessel Humans lcsh:RG1-991 Mastectomy Retrospective Studies Implant-based breast reconstruction Immediate breast reconstruction business.industry lcsh:Public aspects of medicine Obstetrics and Gynecology lcsh:RA1-1270 General Medicine medicine.disease Surgery Radiation therapy medicine.anatomical_structure Risk factors Reproductive Medicine 030220 oncology & carcinogenesis Implant Neoplasm Recurrence Local Breast reconstruction business Research Article Follow-Up Studies |
| Zdroj: | BMC Women's Health BMC Women's Health, Vol 21, Iss 1, Pp 1-12 (2021) |
| ISSN: | 1472-6874 |
| DOI: | 10.1186/s12905-021-01287-4 |
| Popis: | Background The number of patients desiring implant-based breast reconstruction has been increasing. While local recurrence is observed in patients with breast reconstruction, only a few reports have focused on the risk factors for local recurrence and the prognosis after developing local recurrence. Methods We analyzed 387 patients who underwent implant-based breast reconstruction during the period from 2004 to 2017 in Hiroshima City Hospital. We retrospectively examined the risk factors for local recurrence and the outcomes of patients developing such recurrence after implant-based breast reconstruction. Results The median follow-up time was 59 months. The local recurrence rate was 3.1% (n = 12). The most common reason for detecting local recurrence was a palpable mass. Four patients with local recurrence had recurrence involving the skin just above the primary lesion and needle biopsy tract. All patients with local recurrence received surgery and systemic therapy and most patients received radiation therapy, all have remained free of new recurrence to date. Multivariate analysis showed lymphatic vessel invasion (HR, 6.63; 95% CI, 1.40–31.36; p = 0.017) and positive or p = 0.047) to be associated with significantly increased risk of local recurrence. Conclusions The risk factors for local recurrence following implant-based breast reconstruction were lymphatic vessel invasion and positive or |
| Databáze: | OpenAIRE |
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