Outcome of all-comers with STEMI based on the grade of ischemia in the presenting ECG
Autor: | Kjell Nikus, Kimmo Koivula, Markku Eskola, Yochai Birnbaum, Heini Huhtala, Juho Viikilä, Jyrki Lilleberg |
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Přispěvatelé: | Department of Medicine, Kardiologian yksikkö, Clinicum, HUS Heart and Lung Center, Yhteiskuntatieteiden tiedekunta - Faculty of Social Sciences, University of Tampere |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_treatment TERMINAL PORTION 030204 cardiovascular system & hematology Severity of Illness Index Electrocardiography 0302 clinical medicine ST-SEGMENT ELEVATION 030212 general & internal medicine Myocardial infarction medicine.diagnostic_test biology Sisätaudit - Internal medicine Thrombolysis DANAMI-2 TRIAL Prognosis Grade of ischemia 3. Good health ST-elevation myocardial infarction Cardiology Female Cardiology and Cardiovascular Medicine medicine.medical_specialty ACUTE MYOCARDIAL-INFARCTION Myocardial ischemia Biolääketieteet - Biomedicine Ischemia PERCUTANEOUS CORONARY INTERVENTION QRS 03 medical and health sciences QRS complex Angioplasty Internal medicine medicine Humans cardiovascular diseases Mortality ANGIOPLASTY ADMISSION ELECTROCARDIOGRAM THROMBOLYSIS DISTORTION business.industry Percutaneous coronary intervention medicine.disease Troponin 3121 General medicine internal medicine and other clinical medicine biology.protein ST Elevation Myocardial Infarction business |
Popis: | Background: Grade 3 ischemia (G3I) in the 12 lead electrocardiogram (ECG) predicts poor outcome in patients with ST-elevation myocardial infarction (STEMI). The outcome of G3I in "real-life" patient cohorts is unclear. Methods: The aim of the study was to establish the prognostic significance of grade 2 ischemia (G2I), G3I and the STEMI patients excluded from ischemia grading (No grade of ischemia, NG) in a real-life patient population. We assessed in-hospital, 30-day and 1-year mortality as well as other endpoints. Results: The NG patients had more comorbidities and longer treatment delays than the two other groups. Shortterm and 1-year mortality were highest in patients with NG and lowest in patients with G2I. Maximum troponin level was highest in G3I, followed by NG and G2I. In logistic regression multivariable analysis, NG was independently associated with 1-year mortality. Conclusions: NG predicted poor outcome in STEMI patients. G2I predicted relatively favorable outcome. (C) 2018 Elsevier Inc. All rights reserved. |
Databáze: | OpenAIRE |
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