Outcome of all-comers with STEMI based on the grade of ischemia in the presenting ECG

Autor: Kjell Nikus, Kimmo Koivula, Markku Eskola, Yochai Birnbaum, Heini Huhtala, Juho Viikilä, Jyrki Lilleberg
Přispěvatelé: Department of Medicine, Kardiologian yksikkö, Clinicum, HUS Heart and Lung Center, Yhteiskuntatieteiden tiedekunta - Faculty of Social Sciences, University of Tampere
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
medicine.medical_treatment
TERMINAL PORTION
030204 cardiovascular system & hematology
Severity of Illness Index
Electrocardiography
0302 clinical medicine
ST-SEGMENT ELEVATION
030212 general & internal medicine
Myocardial infarction
medicine.diagnostic_test
biology
Sisätaudit - Internal medicine
Thrombolysis
DANAMI-2 TRIAL
Prognosis
Grade of ischemia
3. Good health
ST-elevation myocardial infarction
Cardiology
Female
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
ACUTE MYOCARDIAL-INFARCTION
Myocardial ischemia
Biolääketieteet - Biomedicine
Ischemia
PERCUTANEOUS CORONARY INTERVENTION
QRS
03 medical and health sciences
QRS complex
Angioplasty
Internal medicine
medicine
Humans
cardiovascular diseases
Mortality
ANGIOPLASTY
ADMISSION ELECTROCARDIOGRAM
THROMBOLYSIS
DISTORTION
business.industry
Percutaneous coronary intervention
medicine.disease
Troponin
3121 General medicine
internal medicine and other clinical medicine
biology.protein
ST Elevation Myocardial Infarction
business
Popis: Background: Grade 3 ischemia (G3I) in the 12 lead electrocardiogram (ECG) predicts poor outcome in patients with ST-elevation myocardial infarction (STEMI). The outcome of G3I in "real-life" patient cohorts is unclear. Methods: The aim of the study was to establish the prognostic significance of grade 2 ischemia (G2I), G3I and the STEMI patients excluded from ischemia grading (No grade of ischemia, NG) in a real-life patient population. We assessed in-hospital, 30-day and 1-year mortality as well as other endpoints. Results: The NG patients had more comorbidities and longer treatment delays than the two other groups. Shortterm and 1-year mortality were highest in patients with NG and lowest in patients with G2I. Maximum troponin level was highest in G3I, followed by NG and G2I. In logistic regression multivariable analysis, NG was independently associated with 1-year mortality. Conclusions: NG predicted poor outcome in STEMI patients. G2I predicted relatively favorable outcome. (C) 2018 Elsevier Inc. All rights reserved.
Databáze: OpenAIRE
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