Skin vascular reactivity in healthy subjects: influence of hormonal status
| Autor: | A. Theeuwes, M. L. Bartelink, T. Thien, A. De Wit, H.C.H. Wollersheim |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Physiology Population Blood Pressure Contraceptives Oral Hormonal Fingers Vascular reactivity Physiology (medical) Internal medicine medicine Humans Endocrine system education Skin education.field_of_study Postmenopausal women integumentary system business.industry Healthy subjects Estrogens Middle Aged medicine.disease Hormones Menopause Endocrinology medicine.anatomical_structure Regional Blood Flow Vasoconstriction Regression Analysis Female Progestins Skin Temperature business Hormone Blood vessel |
| Zdroj: | Journal of Applied Physiology. 74:727-732 |
| ISSN: | 1522-1601 8750-7587 |
| Popis: | To investigate the influence of the hormonal status on skin vascular reactivity, 18 males, 18 women using oral contraceptives (oc), 17 premenopausal, and 18 postmenopausal women were studied. Finger skin temperature (FST, in degrees C) and laser Doppler flux (LDF, in perfusion units) were measured during heating (45 degrees C water bath) and cooling (15 degrees C) followed by a subsequent recovery period. Maximal heat-induced vasodilation was significantly higher in women using oc and in premenopausal women when compared with males. During cooling, FST and LDF were significantly higher in males compared with women using oc and premenopausal women, respectively. FST was also higher in postmenopausal women than in women using oc. During recovery, FST and LDF were significantly higher in males than in women using oc, and LDF was also higher in males than in premenopausal women. These findings are consistent with a less pronounced and less prolonged cold-induced vasoconstriction in males. Other hemodynamic (blood pressure or heart rate) or biological factors (age, amount of subcutaneous fat, hand volume, or body mass index) that possibly influence peripheral blood flow were found not to influence the results. The observed differences in vascular reactivity toward temperature changes between subjects with a different hormonal status suggest that sex hormones influence finger skin perfusion. |
| Databáze: | OpenAIRE |
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