False-negative RT-PCR in SARS-CoV-2 disease: experience from an Italian COVID-19 unit
| Autor: | Paolo Palange, Alessandra Iacovelli, Ilaria Menichini, Elda Graziani, Marcello Di Paolo, Claudio Maria Mastroianni, Martina Carnevalini, Federica Olmati, Alessandra Oliva |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty 2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rt-pcr Original Research Letters lcsh:R lcsh:Medicine covid-19 sensitivity Disease 03 medical and health sciences 0302 clinical medicine Real-time polymerase chain reaction 030228 respiratory system Internal medicine medicine 030212 general & internal medicine business |
| Zdroj: | ERJ Open Research, Vol 6, Iss 2 (2020) ERJ Open Research article-version (VoR) Version of Record |
| ISSN: | 2312-0541 |
| Popis: | As of 25 May 2020, a total of 5 304 772 laboratory-confirmed cases and 342 029 deaths due to coronavirus diseases 2019 (COVID-19) have been reported worldwide [1], with the USA, Russia and Brazil being the most involved countries. In the absence of a specific treatment with established efficacy, and while waiting for the development of an effective and safe vaccine, prompt identification and immediate isolation of infected subjects still represent the most important countermeasures to stem the exponential rise in COVID-19 cases and related deaths. False-negative cases of #COVID19 are being increasingly reported. Laboratory diagnosis through RT-PCR testing alone lacks adequate sensitivity to be recommended as the only valid criterion to confirm COVID-19 diagnosis. https://bit.ly/2BLFnEe |
| Databáze: | OpenAIRE |
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