Quality of life of COVID-19 critically ill survivors after ICU discharge: 90 days follow-up
| Autor: | Mirco Leo, Harri Sintonen, Irene Cavalli, Vanni Agnoletti, Emanuela Giampalma, Maurizio Fusari, Cristiana Laici, Andrea Castelli, Chiara Capozzi, Irene Ottaviani, Andrea Marudi, Carlo Alberto Mazzoli, Tommaso Tonetti, Iacopo Cappellini, Stefania Taddei, Federica Damiani, Carlo Alberto Volta, Gianluca Zani, Raffaella Papa, Filippo Becherucci, Lorenzo Gamberini, Savino Spadaro, Davide Colombo, Davide Allegri, Gaetano Scaramuzzo, Antonella Potalivo, Giuseppe Nardi, Maria Concetta Lanza, Elisabetta Bertellini, Giovanni Gordini, Federico Crimaldi, Vito Marco Ranieri, Emanuele Russo |
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| Přispěvatelé: | Gamberini L., Mazzoli C.A., Sintonen H., Colombo D., Scaramuzzo G., Allegri D., Tonetti T., Zani G., Capozzi C., Giampalma E., Agnoletti V., Becherucci F., Bertellini E., Castelli A., Cappellini I., Cavalli I., Crimaldi F., Damiani F., Fusari M., Gordini G., Laici C., Lanza M.C., Leo M., Marudi A., Nardi G., Ottaviani I., Papa R., Potalivo A., Ranieri V.M., Russo E., Taddei S., Volta C.A., Spadaro S., Clinicum, Harri Sintonen Research Group, Department of Public Health |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty ARDS Coronavirus disease 2019 (COVID-19) Critical Illness medicine.medical_treatment Health-related quality of life Coronaviru Disease Severity of Illness Index Article NO law.invention Quality of life law medicine Humans Survivors Aged Mechanical ventilation Respiratory Distress Syndrome Acute respiratory distress syndrome SARS-CoV-2 business.industry Public Health Environmental and Occupational Health COVID-19 15D instrument Coronavirus Middle Aged medicine.disease Intensive care unit Patient Discharge humanities Intensive Care Units 3121 General medicine internal medicine and other clinical medicine Emergency medicine Cohort Quality of Life Female Icu discharge business Follow-Up Studies |
| Zdroj: | Quality of Life Research |
| Popis: | Purpose The onset of the coronavirus disease 19 (COVID-19) pandemic in Italy induced a dramatic increase in the need for intensive care unit (ICU) beds for a large proportion of patients affected by COVID-19-related acute respiratory distress syndrome (ARDS). The aim of the present study was to describe the health-related quality of life (HRQoL) at 90 days after ICU discharge in a cohort of COVID-19 patients undergoing invasive mechanical ventilation and to compare it with an age and sex-matched sample from the general Italian and Finnish populations. Moreover, the possible associations between clinical, demographic, social factors, and HRQoL were investigated. Methods COVID-19 ARDS survivors from 16 participating ICUs were followed up until 90 days after ICU discharge and the HRQoL was evaluated with the 15D instrument. A parallel cohort of age and sex-matched Italian population from the same geographic areas was interviewed and a third group of matched Finnish population was extracted from the Finnish 2011 National Health survey. A linear regression analysis was performed to evaluate potential associations between the evaluated factors and HRQoL. Results 205 patients answered to the questionnaire. HRQoL of the COVID-19 ARDS patients was significantly lower than the matched populations in both physical and mental dimensions. Age, sex, number of comorbidities, ARDS class, duration of invasive mechanical ventilation, and occupational status were found to be significant determinants of the 90 days HRQoL. Clinical severity at ICU admission was poorly correlated to HRQoL. Conclusion COVID-19-related ARDS survivors at 90 days after ICU discharge present a significant reduction both on physical and psychological dimensions of HRQoL measured with the 15D instrument. Trial Registration: NCT04411459. Supplementary Information The online version contains supplementary material available at 10.1007/s11136-021-02865-7. |
| Databáze: | OpenAIRE |
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