Chromium-induced hyperglycemia in the rat
| Autor: | T. Ghafghazi, A. Maghbareh, R. Barnett |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Blood Glucose
Chromium Male medicine.medical_specialty Time Factors business.industry Adrenalectomy medicine.medical_treatment chemistry.chemical_element Glucose Tolerance Test Toxicology Diet Rats Endocrinology chemistry Internal medicine medicine Animals Insulin Insulin hypoglycemia business Hyperglycemic agent |
| Zdroj: | Toxicology. 12:47-52 |
| ISSN: | 0300-483X |
| DOI: | 10.1016/0300-483x(79)90031-3 |
| Popis: | The acute administration of chromium chloride (Cr) produces hyperglycemia in rats. Adrenalectomy prevents the hyperglycemic effect but not the glucose intolerance. Subacute exposure of rats to Cr for 7–23 days does not change the testing glucose nor is there an acute or subacute effect on tolerance to glucose load. Administration of Cr does not influence acute insulin hypoglycemia. Thus contrary to Cr deficient animal, at the concentrations tested, Cr appears to be a hyperglycemic agent to rats with minimal subacute effects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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