Impact of valvuloarterial impedance on left ventricular reverse remodeling after aortic valve neocuspidization

Autor: Naoki Yamamoto, Hisato Ito, Kentaro Inoue, Ayano Futsuki, Koji Hirano, Yu Shomura, Yasuhisa Ozu, Yoshihiko Katayama, Takuya Komada, Motoshi Takao
Rok vydání: 2021
Předmět:
Zdroj: Journal of Cardiothoracic Surgery
Journal of Cardiothoracic Surgery, Vol 17, Iss 1, Pp 1-9 (2022)
ISSN: 1749-8090
Popis: Background Aortic valve neocuspidization (AVNeo) has emerged as a promising aortic valve procedure, and is expected to have a larger effective orifice area (EOA) than commercially available bioprostheses. It is, however, unclear which indices could facilitate left ventricular (LV) reverse remodeling after AVNeo. The aim of this study is to verify the impact of global left ventricular afterload on the LV reverse remodeling following AVNeo. Methods Data-available consecutive 38 patients (median age, 77; interquartile range, 72.8–82.0) undergoing AVNeo for severe aortic stenosis were enrolled in this study. Preoperative and the last follow-up echocardiographic data were retrospectively analyzed including the valvuloarterial impedance (Zva), a marker of global LV afterload. Reduction in LV geometry index (LVGI) and relative wall thickness (RWT) were used as an indicator for LV reverse remodeling. Results The Zva reduced in 24 patients (63.2%) during the follow-up period (median, 12 months). Reduction in Zva significantly correlated to improvement of LV geometry (LVGI (r = 0.400, p = 0.013) and RWT (r = 0.627, p p = 0.957), or RWT (r = 0.105, p = 0.529)). The reduction in Zva was the multivariate predictor of LV reverse remodeling. Conclusions Low global LV afterload led to significant LV reverse remodeling even after AVNeo, which could achieve better valve performance than the conventional bioprostheses.
Databáze: OpenAIRE
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