Impact of type II diabetes and gender on major clinical events after percutaneous coronary intervention
| Autor: | Mohammad Javad Zibaeenezhad, Mehrab Sayadi, Paolo Verdecchia, Khosrow Safaei, Zahra Elyaspour, Iman Razeghian-Jahromi |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Type 2 diabetes Coronary Artery Disease Coronary artery disease 03 medical and health sciences 0302 clinical medicine Percutaneous Coronary Intervention Risk Factors Internal medicine Diabetes mellitus Internal Medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Myocardial infarction Nutrition and Dietetics business.industry Stent Percutaneous coronary intervention Drug-Eluting Stents medicine.disease Treatment Outcome Diabetes Mellitus Type 2 Conventional PCI Cardiology Female Family Practice business Mace |
| Zdroj: | Primary care diabetes. 15(2) |
| ISSN: | 1878-0210 |
| Popis: | Aims Incidence of type 2 diabetes is markedly rising worldwide. Some studies suggest that the occurrence of major adverse cardiac events (MACE) after PCI is different in men and women, but data are conflicting. Methods We studied patients with stable coronary artery disease (CAD) who underwent PCI between years 2000 and 2017. Patients with primary PCI were excluded. Drug-eluting stent (DES) and dual antiplatelet therapy were administered in all patients. We followed these patients for a mean of 68 months. MACE as a composite of coronary revascularization, myocardial infarction or cardiovascular death was sought in three time windows. Results We studied 1799 patients, 29.6% of whom with diabetes. Women were 52%. In multivariate analyses, there were no significant differences in the risk of MACE between diabetic and non-diabetic patients, as well as between men and women, neither in different time windows, nor in the whole duration of follow-up. The components of MACE did not show any significant differences between diabetic and non-diabetic patients, as well as between the genders. Conclusion In our patients with stable CAD who received a modern therapeutic management after PCI, neither type 2 diabetes nor gender were associated with an excess risk of MACE. |
| Databáze: | OpenAIRE |
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