Prevalence and vaccination coverage of Hepatitis B among healthcare workers in Cameroon: A national seroprevalence survey

Autor:	Georges Alain Etoundi Mballa, Florence Zeh, Yap Boum, Rachel Essaka Evoue, Rose Mbaye, Lucrèce Eteki, Rodrigue Ntone, Brian Bongwong, Richard Njouom, Chanceline Bilounga Ndongo, Jennifer S. Chen, Olivier Donfack, Magloire Biwole Sida, Georges Nguefack-Tsague, Mark J. Siedner
Rok vydání:	2018
Předmět:	Adult Male medicine.medical_specialty Vaccination Coverage Health Personnel 030231 tropical medicine medicine.disease_cause Article Young Adult 03 medical and health sciences symbols.namesake 0302 clinical medicine Risk Factors Surveys and Questionnaires Virology Internal medicine Health care Prevalence Humans Medicine Seroprevalence Hepatitis B Vaccines Cameroon 030212 general & internal medicine Poisson regression Hepatitis B virus Hepatology business.industry Risk of infection virus diseases Middle Aged Hepatitis B medicine.disease Vaccine efficacy Hospitals digestive system diseases Vaccination Cross-Sectional Studies Infectious Diseases symbols Female business
Zdroj:	Journal of Viral Hepatitis. 25:1582-1587
ISSN:	1352-0504
Popis:	INTRODUCTION: Hepatitis B virus (HBV) infection is hyperendemic in Cameroon, and health care workers (HCWs) are at high-risk of infection. We aimed to assess prevalence, risk factors and vaccine coverage of HBV infection among HCWs in Cameroon. METHODS: We conducted a cross-sectional study in 16 hospitals across all regions of Cameroon. HCWs were tested for HBV using rapid diagnostic tests (RDT). We collected data on socio-demographics and HBV vaccination status. We estimated prevalence of HBV and used Poisson regression models with robust standard errors to model the prevalence ratios of HBV positivity between covariates. RESULTS: We enrolled 1,824 of 1,836 eligible HCWs (97.5%). The mean age was 34 (SD: 10) years, 65.3% (n=1787) were women, and 11.4% (n=1747) had three or more doses of the HBV vaccine. Overall, we found a HBV prevalence of 8.7% (95% CI: 5.2 – 14.3%). Patient transporters had the highest crude prevalence (14.3%; 95%CI: 5.4–32.9%), whereas medical doctors had the lowest (3.2%; 95%CI: 0.8%−12.1%). The Far North Region had the highest prevalence of HBV (24.0%; 95%CI: 18.3%−30.8%). HBV prevalence decreased with increasing doses of the HBV vaccine (10.3% for no doses vs 3.5% for three or more doses; P
Databáze:	OpenAIRE
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